Drug-induced esophageal injury with an occult vascular ring

Esophageal stenosis due to vascular ring.

a E u s a o 6-year-old boy was referred for follow-up of a ventricular septal defect, which was first diagnosed when he was a neonate. Cardiac catheterization performed t 7 months of age revealed an aberrant left subclavian artery rising from the right aortic arch. Recurrent respiratory inection that caused stridor and/or wheezing occurred in early nfanthood, but it was deemed not related to th...

22q11.2 microduplication syndrome with associated esophageal atresia/tracheo‐esophageal fistula and vascular ring

This case report describes a patient with a 22q11.2 duplication. His features, which include VACTERL association with an esophageal atresia/tracheo-esophageal fistula and a vascular ring, expand the previously described phenotype for this duplication.

Drug-induced vascular injury--a quest for biomarkers.

Drug-induced oesophageal injury.

'Blackett, R L, et al, British Journal of Surgery, 1978, 65, 393. 2 Wilmore, D W, and Dudrick, S J, Archives of Surgery, 1969, 98, 256. 3 Durskin, M S, and Seigal, P D, 7ournal of the American Medical Association, 1963, 185, 966. 'Copeland, F M, et al, Surgery, Gynecology, and Obstetrics, 1974, 138, 377. 6Horshal, V L, Ause, R G, and Hoskins, P A, Archives of Surgery, 1971, 102, 353. Tanner, W ...

A bilayer small diameter in vitro vascular model for evaluation of drug induced vascular injury.

In pre-clinical safety studies, drug-induced vascular injury (DIVI) is defined as an adverse response to a drug characterized by degenerative and hyperplastic changes of endothelial cells and vascular smooth muscle cells. Inflammation may also be seen, along with extravasation of red blood cells into the smooth muscle layer (i.e., hemorrhage). Drugs that cause DIVI are often discontinued from d...